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6791484 
Journal Article 
Coronary heart disease mortality in relation to dietary, lifestyle and biochemical risk factors in the countries of the Seven Countries Study: a secondary dataset analysis 
Papandreou, C; Tuomilehto, H; , 
2014 
Yes 
Journal of Human Nutrition and Dietetics
ISSN: 0952-3871
EISSN: 1365-277X 
WILEY 
HOBOKEN 
168-175 
24313566 
WOS:000333018500008 
BackgroundThe present study explored coronary heart disease (CHD) mortality rates in 2011 in countries that participated in the Seven Countries Study (SCS) in relation to several dietary and anthropometric/biochemical risk factors. Special focus was given to Crete and the Ionian Islands.MethodsThis was a cross-sectional study of secondary analysis of databases using data from the World Health Organization, the Food and Agriculture Organization database and the Greek National Cadaster and Cartography Organization. Geographically weighted regression was applied to identify the high-risk regions in relation to the significant factors.ResultsCrete, the Ionian Islands and Japan had the lowest mortality rates (28.9, 30.1 and 31.2 deaths/100000 people, respectively) in contrast to Serbia/Montenegro that presented the highest rates (105.1 deaths/100000 people). Diet, physical inactivity and hypertension were found to be the most significant factors in the model (P<0.05). Regions of no risk were Crete, Ionian Islands and Japan (exponent B=0.65; 95% confidence interval=0.293-0.942; P<0.001), whereas Serbia/Montenegro and Finland were identified as high-risk areas with a 2.97-fold higher probability for CHD mortality (95% confidence interval=1.736-4.028; P<0.001).ConclusionsObserved patterns of CHD mortality and related factors may be helpful for appropriate management by health planners when aiming to reduce its prevalence, particularly in high-risk areas.