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Citation
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HERO ID
6797098
Reference Type
Journal Article
Title
DNA methylation in zebrafish
Author(s)
Goll, MG; Halpern, ME
Year
2011
Volume
101
Page Numbers
193-218
Language
English
PMID
21507352
DOI
10.1016/B978-0-12-387685-0.00005-6
Web of Science Id
WOS:000290238400005
Abstract
DNA methylation is crucial for normal development and cellular differentiation in many large-genome eukaryotes. The small tropical freshwater fish Danio rerio (zebrafish) has recently emerged as a powerful system for the study of DNA methylation, especially in the context of development. This review summarizes our current knowledge of DNA methylation in zebrafish and provides evidence for the general conservation of this system with mammals. In addition, emerging strategies are highlighted that use the fish model to address some of the key unanswered questions in DNA methylation research.
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