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6810026 
Journal Article 
Chemopreventive effect of quercetin, a natural dietary flavonoid on prostate cancer in in vivo model 
Sharmila, G; Bhat, FA; Arunkumar, R; Elumalai, P; Singh, PR; Senthilkumar, K; Arunakaran, J 
2014 
Yes 
Clinical Nutrition
ISSN: 0261-5614
EISSN: 1532-1983 
33 
4 
718-726 
English 
24080313 
WOS:000338810300022 
Prostate cancer is one of the frequently diagnosed cancers in men. Increased Growth factor IGF-1/IGF-1R axis activation mediated by both PI3K/Akt or RAF/MEK/ERK system and AR expression remains important in the development and progression of prostate cancer. Targeting such system by dietary agents quercetin in vivo model could aid its application in both treatment as well as prevention of prostate cancer. 
Quercetin; Antioxidant enzymes; Prostate cancer; Cell survival; Proliferation; Apoptosis