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6817571 
Journal Article 
Phytotoxic and antifungal metabolites from Curvularia sp. FH01 isolated from the gut of Atractomorpha sinensis 
Zhang, YL; Kong, LC; Jiang, DH; Yin, CP; Cai, QM; Chen, Q; Zheng, JY 
2011 
Yes 
Bioresource Technology
ISSN: 0960-8524
EISSN: 1873-2976 
102 
3 
3575-3577 
English 
21035325 
WOS:000286904500206 
Two main phytotoxic and antifungal phthalic acid butyl isobutyl ester (1) and radicinin (2) were isolated from the culture of Curvularia sp. FH01, a fungus residing in the Atractomorpha sinensis gut. The structures of isolated metabolites were established on the basis of spectral analysis. Metabolites 1 and 2 exhibited significant phytotoxic activity against the radical growth of Echinochloa crusgalli with their IC(50) values of 61.9 and 5.9 μg/mL, respectively, which were comparable to that 2,4-dichlorophenoxyacetic acid (2.0 μg/mL) used as a positive control. The antifungal test results showed that compound 2 possessed strong antifungal activity against Magnaporthe grisea (IC(50)=16.3 μg/mL) and Valsa mali (IC(50)=18.2 μg/mL). The findings of the present study suggest that bioactive properties of the fungus FH01 can be attributed to its major components, phthalic acid butyl isobutyl ester and radicinin, and both agents have a potential to be used as herbicide and fungicide. 
Curvularia sp.; Phthalic acid butyl isobutyl ester; Radicinin; Phytotoxic activity; Antifungal activity