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6852477 
Journal Article 
Facile and general syntheses of 1-alkyltoxoflavin and 8-alkylfervenulin derivatives of biological significance by the regiospecific alkylation of reumycin (1-demethyltoxoflavin, 8-demethyl-fervenulin) derivatives 
Nagamatsu, T; Nagamatsu, T; Yamasaki, H; Yamasaki, H 
1997 
Yes 
Heterocycles
ISSN: 0385-5414 
45 
4 
643-650 
WOS:A1997XG65200001 
Regiospecific alkylation of reumycins (6) under alkaline conditions with a dialkyl sulfate or alkyl halide in dioxane and in DMF to provide 1-alkyltoxoflavins (5) of biological significance and 8-alkylfervenulins (7), respectively, is described.<