The style, spatial-temporal distribution, formation and evolution of mineral resources are closely related to the nature and evolution of the crust and the development of the tectonic framework. Due to the complexity of geological settings in Chinese continent, various types of metallogenic systematics are well developed, such as Proterozoic rift, collision, plume, low-temperature metallogenic systematics. China is rich in Mo, W, Sn and REE but short of Cu, high-grade Fe, Al and sylvite. It also lacks of Early Precambrian mineral deposits, and has the outbreak of Yanshanian mineralization. The relationship between these characteristics of mineralization, the formation and evolution features of small continental blocks in China, and accretionary collage of microcontinents is still unclear. In this paper, we try to summarize and reveal the formation and evolution features of small continental blocks in China, the double-directions accretionary collage orogenesis in Central Asian Orogenic Belt (CAOB), and the evolution of Proto-Paleo-New Tethyan Ocean and succeden continent-arc collision orogenic belt as well as decraton of North China Craton (NCC) during Late Mesozoic, and their relationship to mineralizations. The features are as follows:(1) The mass ratio of platform over orogens in Chinese continent (about 3:7) is smaller than that of the bulk Earth (about 7:3). And China has the separated and small areas of Archean crust. The consolidation of the Chinese continental crust also took place over 500 similar to 1000Myr later than the shield areas elsewhere in the world. All these features resulted in the lack of rich BIF deposits, Archean giant VMS Cu-Zn deposits and Proterozoic rift-related Zambia-style giant Cu deposits. (2) We conclude the characteristics of the metallogenesis and their connection with the styles, evolution and overlapping of orogens along the North China, Tarim and Yangtze platforms and crustal evolution. The continental crust of China was formed through the accretion of several blocks. With the old masifs as the core and the orogen system of different ages as the margins, it progressively accreted and grew outwards, leading to the migration of volcanic intrusive activies, sites of sedimentation and related mineralization towards the margins of the old orogen and basin with the progress of time. (3) The Central Asian Orogenic Belt has experienced the Paleozoic accretionary collage of microcontinents, and Mesozoic-Cenozoic intra-continental orogenesis and basin-and-mountain system, thus the CAOB can host arc-related mineral deposits (e.g. ophiolite chromite deposit, porphyry Cu-Au-Mo deposit and volcanic-host massive sulfide deposit), collision-related ore deposits (e.g. orogenic gold deposit, and asbestos, talc and mica deposits), ore deposits related to unusual overlapping CAOB by Early Permian Tarim plume (magmatic Cu-Ni-Co deposit), and intra-continent extensional environment (such as, porphyry Mo deposit, hydrothermal Au deposit and pegamatite rare metals, sandstone U and sylvite deposits). (4) Numerous large- and super-large porphyry Cu-Au-Mo deposits, MVT Pb-Zn and ophiolite Cr deposits are generated in the evolution of Proto-Paleo-New Tethyan oceanic subduction along the Qilian, Kunlen to Bangongcuo-Nujiang and Yarlung Zangbo sutures and the process of the India-Asia continental collision in the Qinghai-Tibetan orogen. (5) Crustal movements in China, especially in East China, were ubiquitious, frenquent and rather strong, and these chacteristics are rarely seen in other parts of the world.The massive magmatism and Au, Cu, Mo and light rare earth elements deposits around the NCC occurred in the Late Mesozoic, accompanied with the significant change in the nature of NCC and the decraton of North China lithosphere. A large number of world-class W, Sn and Mo deposits occured with high-evolved granitoids in the highly mature East China continent, related to the polycyclic nature of the tectonism, magmatism, and sedimentation in China. As all the metallogenic features are genetically associated with the evolution of continental crust and multi-stage orogens, the exploration plans in China shoud pay much more attention to the evolution features of small continental blocks, and accretionary collage of microcontinents. Finally, we suggest several significant questions in the areas of continental metallogeny and the futher exploration in China.