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6879014 
Journal Article 
Some new organotin(IV) complexes of biologically important semicarbazones and thiosemicarbazones 
Sharma, S; Bedi, M; Varshney, S; Varshney, AK; , 
2012 
Yes 
Journal of the Indian Chemical Society
ISSN: 0019-4522 
SCIENTIFIC PUBL-INDIA 
JODHPUR 
41-50 
WOS:000302332800006 
The present paper is a report on the synthesis of some new organotin(IV) complexes by the reactions of bis(tributyltin)oxide and semicarbazones/thiosemicarbazones using benzene as reaction medium. Semicarbazones and thiosemicarbazones are prepared by condensation of 4-acetylbiphenyl, 2-acetylflurene, 9-acetylanthracene, anthraldehyde and 4-flouro-acetophenone with semicarbazide hydrochloride and thiosemicarbazide in ethanol. Monomeric nature of these complexes has been confirmed on the basis of their molecular weight determination. Purity of the complexes has been confirmed by thin layer chromatography. Non electrolytic nature of complexes has been detected by their conductance measurement. The bonding pattern and geometry of tin complexes are characterized by spectroscopic studies (IR, UV, H-1 NMR, C-13 NMR, Sn-119 NMR, spectral studies). The investigated compounds and the ligands were tested against bacterial and fungal species. The bacteria and fungi used in these investigations are Escherichia coli, Staphylococus aureus, Proteus milamilis, Bacillus thurengiensis (bacteria) and F. oxysporum, A. flavus, A. niger, R. phaseoli (fungi). The metal complexes have higher activity than the free ligands.