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6916361 
Journal Article 
The Atypical Onset with Pleural Effusion of an Indolent Lymphoma Case report and review of literature 
Fortofoiu, MC; Dobrinescu, AG; Rotaru, TL; Padureanu, V; Dobrinescu, A; Bala, S; Sas, T; Mita, A; Fortofoiu, M 
2019 
1 
Revista de Chimie
ISSN: 0034-7752
EISSN: 2668-8212 
70 
10 
3708-3710 
English 
WOS:000500795900056 
The goal of pleural fluid assessment is to establish with certainty its etiology and major challenge is the etiologic diagnosis precocity. Pleural effusion as the first and the only event in the onset of non-Hodgkin lymphoma is atypically in the absence of other signs and symptoms. Follicular lymphoma (FL) also called indolent lymphoma the most frequent is a low-grade non-Hodgkin’s lymphoma (NHL). In patients with indolent lymphoma affecting the pleura and pericardium is atypical and appears only in aggressive forms, so the onset with pleural effusion is unusual. Serous effusions may occur from onset or during evolution of various subtypes of T cell originated lymphomas or high-grade B cell lymphomas. Primary pleural lymphomas (PPL) have been described at patients with human immunodeficiency virus infection; tuberculosis complicated with chronic pyothorax or after exposure to asbestos. Compared to other similar cases previously reported in the medical literature, the novelty of this case is the atypical onset of low grade of indolent B-cells non-Hodgkin with primary pleural effusion in the absence of personal history as well as of another clinical, laboratory and pleural changes. © 2019 SYSCOM 18 S.R.L.. All rights reserved. 
primary pleural effusion; thoracoscopy; non-Hodgkin lymphoma; immunohistochemistry; metabolic remission 
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