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6919746 
Journal Article 
REACTIONS OF NINHYDRIN WITH BENZO[b]THIOPHENES 
Suzue, N; Ishii, Rie; Kamiya, Ryo; Wakabayashi, H; Kobayashi, K; , 
2009 
Yes 
Heterocycles
ISSN: 0385-5414 
PERGAMON-ELSEVIER SCIENCE LTD 
OXFORD 
78 
10 
2467-2475 
English 
WOS:000271145200005 
The reaction of ninhydrin with benzo[b]thiophene in acetic acid in the presence of a small amount of sulfuric acid afforded a novel fluorenone compound fused to benzo[b]thiophene rings. In the reaction using 2,2'-bibenzo[b]thiophene, phthalide conjoined in a spiro framework was unexpectedly isolated along with an isocoumarin derivative which is fused to benzo[b]thiophene and benzene rings. The product related to the latter was obtained in the reaction of 3,3'-bithiophene with ninhydrin. The structures of these novel heterocycles were supported by spectroscopic studies and X-ray crystallography.