Kamura, S; Archer, RJ; Dunderdale, GJ; Hozumi, A; Kohlhauer, M; Boissady, E; Lidouren, F; de Rochefort, L; Nadeau, M; Rambaud, J; Hutin, A; Dubuisson, RM; Martini, G; Pey, WP; Bruneval, PP; Unterkofler, E; Sage, MM; Walti, H; Watts, P; Ricard, C; Berdeaux, A; Mongardon, N; Ghaleh, B; Micheau, P; Tissier, R
Total liquid ventilation (TLV) of the lungs could provide radically new benefits in critically ill patients requiring lung lavage or ultra-fast cooling after cardiac arrest. It consists in an initial filling of the lungs with perfluorocarbons and subsequent tidal ventilation using a dedicated liquid ventilator. Here, we propose a new paradigm for a lung-conservative TLV using pulmonary volumes of perfluorocarbons below functional residual capacity (FRC).