Health & Environmental Research Online (HERO)


Print Feedback Export to File
7001175 
Journal Article 
An insight on superoxide dismutase (SOD) from plants for mammalian health enhancement 
Stephenie, S; Chang, YP; Gnanasekaran, A; Esa, NM; Gnanaraj, C; , 
2020 
Yes 
Journal of Functional Foods
ISSN: 1756-4646 
ELSEVIER 
AMSTERDAM 
68 
WOS:000529829800032 
Superoxide dismutase (SOD) is an antioxidant enzyme functional for physiological defense strategies in animals and plants against free radicals and reactive oxygen species (ROS) generated from biotic and abiotic stress. Supplementation of SOD from plants in mammalian diet is a new approach in terms of health improvement against pathological conditions. There is a research gap about the feasibility of including plant-derived SOD in animal diet as health enhancer due to poor bioavailability upon oral administration. Commercially available wheat gliadin encapsulated melon SOD has been proven to enhance mammalian health, but gluten/gliadin intolerance in certain animals and human may limit its marketability. Therefore, this review aims to highlight the sources of SOD from underutilized plants and potential encapsulation of SOD using soluble dietary fibers to be incorporated in animal diet as health enhancing supplements. This review provides a sustainable solution for the development of therapeutic approaches in agricultural industry. 
Superoxide dismutase; Oxidative stress; Bioavailability; Encapsulation; Dietary fiber