Health & Environmental Research Online (HERO)


Print Feedback Export to File
7001763 
Journal Article 
Magnetic Nanoparticles in Cancer Therapy and Diagnosis 
Farzin, Ali; Etesami, SA; Quint, J; Memic, A; Tamayol, Ali; , 
2020 
1 
Advanced Healthcare Materials
EISSN: 2192-2659 
WILEY 
HOBOKEN 
9 
9 
32196144 
WOS:000520852700001 
There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface-area-to-volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can function as contrast agents for magnetic resonance imaging (MRI) and can improve the sensitivity of biosensors and diagnostic tools. Recent advancements in nanotechnology have resulted in the realization of the next generation of MNPs suitable for these and other biomedical applications. This review discusses methods utilized for the fabrication and engineering of MNPs. Recent progress in the use of MNPs for hyperthermia therapy, controlling drug release, MRI, and biosensing is also critically reviewed. Finally, challenges in the field and potential opportunities for the use of MNPs toward improving their properties are discussed. 
cancer detection; cancer therapy; drug delivery; hyperthermia; magnetic nanoparticles