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7022982 
Journal Article 
Mast Cell Activation Syndrome: Tools for Diagnosis and Differential Diagnosis 
Weiler, CR 
2020 
Yes 
Journal of Allergy and Clinical Immunology. In Practice
ISSN: 2213-2198
EISSN: 2213-2201 
8 
2 
498-506 
English 
31470118 
WOS:000512964500008 
The current consensus diagnostic criteria for mast cell activation syndrome(s) (MCAS[s]) were first established in 2012 and updated in 2019. This diagnosis has been attached to multiple medical conditions not intended as part of the diagnosis. In this article, the diagnostic criteria are reviewed and other diseases in the differential diagnosis outlined. The goal of this review is to provide a tool for evaluation of patients with conditions that can mimic MCAS. Furthermore, the potential role for hereditary alpha-tryptasemia in this group of disorders is discussed. 
Mast cell activation syndrome (MCAS); Mastocytosis; Tryptase; N-Methylhistamine; Prostaglandin; Leukotriene E-4; Diagnostic criteria of MCAS; Differential diagnosis of MCAS; Hereditary alpha-tryptasemia (HAT); Diagnostic algorithm for MCAS