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7026998 
Journal Article 
Surgical stress index reflects surgical stress in gynaecological laparoscopic day-case surgery 
Ahonen, J; Jokela, R; Uutela, K; Huiku, M; , 
2007 
Yes 
British Journal of Anaesthesia
ISSN: 0007-0912
EISSN: 1471-6771 
ELSEVIER SCI LTD 
OXFORD 
456-461 
English 
17350969 
WOS:000245788900007 
Monitoring of analgesia remains a challenge during general anaesthesia. The surgical stress index (SSI) is derived from the photoplethysmographic waveform amplitude and the heart beat-to-beat interval. We evaluated the ability of SSI to measure surgical stress in patients undergoing gynaecological laparoscopy. Our hypothesis was that while keeping State Entropy (SE) at a predetermined level, SSI would be higher in patients receiving a beta-blocking agent (esmolol) than in those receiving an opioid (remifentanil) during laparoscopy.