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HERO ID
7064227
Reference Type
Journal Article
Title
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery
Author(s)
Legg, LA; Tilney, R; Hsieh, CF; Wu, S; Lundström, E; Rudberg, AS; Kutlubaev, MA; Dennis, M; Soleimani, B; Barugh, A; Hackett, ML; Hankey, GJ; Mead, GE; ,
Year
2019
Is Peer Reviewed?
Yes
Journal
Cochrane Database of Systematic Reviews
ISSN:
1469-493X
Publisher
WILEY
Location
HOBOKEN
Language
English
PMID
31769878
DOI
10.1002/14651858.CD009286.pub3
Web of Science Id
WOS:000504427100035
Abstract
Stroke is a major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression and other mood disorders after stroke. The 2012 Cochrane Review of SSRIs for stroke recovery demonstrated positive effects on recovery, even in people who were not depressed at randomisation. A large trial of fluoxetine for stroke recovery (fluoxetine versus placebo under supervision) has recently been published, and it is now appropriate to update the evidence.
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