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HERO ID
7064854
Reference Type
Journal Article
Title
Icotinib is as efficacious as gefitinib for brain metastasis of EGFR mutated non-small-cell lung cancer
Author(s)
Liu, K; Jiang, G; Zhang, A; Li, Z; Jia, J; ,
Year
2020
Is Peer Reviewed?
Yes
Journal
BMC Cancer
ISSN:
1471-2407
EISSN:
14712407
Publisher
BMC
Location
LONDON
Language
English
PMID
32000711
DOI
10.1186/s12885-020-6543-y
Web of Science Id
WOS:000520409000001
Abstract
The prognosis of non-small-cell lung cancer (NSCLC) with brain metastases is very poor. Currently, therapeutic methods for this patient population include whole-brain radiation therapy (WBRT), surgery, radiosurgery and systemic treatment. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) could be effective on cerebral metastases of mutated NSCLC. However, which EGFR-TKIs is more appropriate is still unknown.
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