Circulating microRNA's as a diagnostic tool for hepatocellular carcinoma in a hyper endemic HIV setting, KwaZulu-Natal, South Africa: a case control study protocol focusing on viral etiology | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7066844

Reference Type

Journal Article

Title

Circulating microRNA's as a diagnostic tool for hepatocellular carcinoma in a hyper endemic HIV setting, KwaZulu-Natal, South Africa: a case control study protocol focusing on viral etiology

Author(s)

Sartorius, K; Sartorius, B; Kramvis, A; Singh, E; Turchinovich, A; Burwinkel, B; Madiba, T; Winkler, CA; ,

Year

2017

Is Peer Reviewed?

Yes

Journal

BMC Cancer
ISSN: 1471-2407
EISSN: 14712407

Publisher

BIOMED CENTRAL LTD

Location

LONDON

Language

English

PMID

29282036

DOI

10.1186/s12885-017-3915-z

Web of Science Id

WOS:000419223800007

Abstract

A wide range of studies has investigated the diagnostic proficiency of extracellular microRNAs (miRNAs) in hepatocellular cancer (HCC). HCC is expected to increase in Sub-Saharan Africa (SSA), due to endemic levels of viral infection (HBV/HIV), ageing and changing lifestyles. This unique aetiological background provides an opportunity for investigating potentially novel circulating miRNAs as biomarkers for HCC in a prospective study in South Africa.