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Journal Article 
Implants in regenerated bone: long-term survival 
Nevins, M; Mellonig, JT; Clem, DS; Reiser, GM; Buser, DA; , 
International Journal of Periodontics & Restorative Dentistry
ISSN: 0198-7569 
This retrospective multicenter study analyzed 526 implants placed and loaded in regenerated bone. Both autogenous and allogeneic bone grafts were used in combination with a barrier membrane to reconstruct bone using either a simultaneous or staged approach. Implants were followed from 6 to more than 74 months postloading. Eight of the implants were lost, for a success rate of 97.5%. The type of graft material did not affect the clinical success of the implants, nor did the use of submerged versus nonsubmerged implants or a staged versus a simultaneous approach. In conclusion, regenerated bone reacted to implant placement in a manner that was clinically similar to native bone.