Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
7075608
Reference Type
Journal Article
Title
Antibacterial and Antioxidant potential of White and Pink Nelumbo Nucifera Gaertn Flowers
Author(s)
Venkatesh, B; Dorai, A; ,
Year
2011
Publisher
INT ASSOC COMPUTER SCIENCE & INFORMATION TECHNOLOGY PRESS-IACSIT PRESS
Location
SINGAPORE
Page Numbers
213-217
Web of Science Id
WOS:000392766100046
Abstract
The recent interest on alternative medicine has taken up great dimensions in changing the health care scenario across the globe. The worldwide interest in medicinal plants reflects recognition of the validity of studying the antimicrobial and antioxidant activity. Hence the present study was carried out to explore antibacterial and antioxidant potential of hydroethanolic extract of both white and pink flowers of Nelumbo nucifera Gaertn (Nelumbonaceae) flower in vitro. The antibacterial activity was screened against different bacterial strains by detecting zone of inhibition and minimum inhibitory concentration (MIC). The zone of inhibition and MIC values were compared with control compared with standard antibiotic disc suggesting their potential as alternatives to orthodox antibiotics in the treatment of infectious caused by these microorganisms. Total antioxidant potential was evaluated in hydroethanolic extract of white Nelumbo nucifera (HEWNN) flower and hydroethanolic extract of pink Nelumbo nucifera (HEPNN) flower by: Ferric reducing antioxidant power (FRAP), Hemoglobin glycosylation,Reducing power and Phosphomolybdenum and compared with the standard ascorbic acid in dose dependent manner. Both HEWNN and HEPNN flower extracts showed maximum activity 16.53 mg and 14.21 mg at 1000 mu g/ml concentration in FRAP assay. Significantly high antioxidant activity (55.5% & 41.6%) was noticed in haemoglobin glycosylation followed reducing power (0.52 & 0.45 Abs). The results suggest that alkaloids, phenols and flavonoids in flowers provide considerable antioxidant activity. However, in comparison with HEPNN flower, HEWNN flower extract exerted effective antibacterial and potent antioxidant activity which can be used as a lead compound for drug development in the future.
Editor(s)
Ying, F;
ISBN
978-981-08-8718-6
Conference Name
International Conference on Bioscience, Biochemistry and Bioinformatics (ICBBB 2011)
Conference Location
Singapore, SINGAPORE
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity