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HERO ID
7088150
Reference Type
Journal Article
Title
The Assessment of Relationship between Fragmented QRS Complex and Left Ventricular Wall Motion Score Index in Patients with ST Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention
Author(s)
Uslu, N; Surgit, O; Erturk, M; Aksu, H; Eksik, A; Gul, M; Cakmak, HA; Atam, Ali; Pusuroglu, H; Satilmisoglu, H; Akkaya, E; Aksu, HU; Kalkan, AliK; ,
Year
2015
Is Peer Reviewed?
Yes
Journal
Annals of Noninvasive Electrocardiology
ISSN:
1082-720X
EISSN:
1542-474X
Publisher
WILEY
Location
HOBOKEN
Page Numbers
148-157
PMID
25041063
DOI
10.1111/anec.12180
Web of Science Id
WOS:000352015500007
Abstract
ObjectivesFragmented QRS (fQRS) has been found to be associated with high mortality and arrhythmic events in acute coronary syndromes. Regional systolic function using wall motion score index (WMSI) is an alternative to left ventricular ejection fraction (LVEF) for the assessment of left ventricular systolic function. The aim of this study was to investigate the relation between the presence of fQRS on admission electrocardiogram (ECG) and WMSI in ST elevation myocardial infarction (STEMI) underwent primary coronary intervention (PCI). The in-hospital and long-term prognostic significance of persistent fQRS was also evaluated.MethodsIn this retrospective study, 542 patients with a diagnose of STEMI underwent primary PCI were included. Study patients were divided into two groups according to the presence (n = 153) or absence (n = 389) of a fQRS on admission ECG.ResultsWMSI was found to be significantly higher in fQRS(+) group compared to the fQRS(-) group (P<0.001). In multivariete analysis, WMSI was found to be an independent predictor of fQRS, and fQRS was inversely associated with LVEF. The in-hospital reinfarction (P=0.003), MACE (P=0.024), intraaortic balloon pump use (P=0.014), and advanced heart failure (P<0.001) were found to be significantly more frequent in the fQRS(+) group. The presence of fQRS on admission was found to be associated with an increase in long-term cardiovascular mortality (P=0.028), and long-term all-cause mortality (P=0.022).ConclusionWMSI was significantly related with the presence of the fQRS, which reflects the linking between impairment of regional left ventricular systolic function and the presence of severe myocardial injury in STEMI.
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