Health & Environmental Research Online (HERO)


Print Feedback Export to File
7090044 
Journal Article 
Biological activities of [1,2,4]triazolo[1,5-a]pyrimidines and analogs 
Pinheiro, S; Pinheiro, EMC; Muri, EMF; Pessoa, JC; Cadorini, MA; Greco, SJ; , 
2020 
1 
Medicinal Chemistry Research
ISSN: 1054-2523
EISSN: 1554-8120 
SPRINGER BIRKHAUSER 
NEW YORK 
1751-1776 
WOS:000554838300002 
The [1,2,4]triazolo[1,5-a]pyrimidines (TPs) comprise an important class of non-naturally occurring small molecules that aroused the interest of researches. This scaffold is present in diverse important structures in agriculture and medicinal chemistry, such as antibacterial, antifungal, antiviral, antiparasitic, and anticancer. As over the decades the development of the chemistry and application of 1,2,4-triazolo[1,5-a]pyrimidines has continued and even accelerated, in this review, we thoroughly discussed the applications of TPs in both agriculture and medicinal chemistry highlighting the significance of this nucleus.[GRAPHICS].