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7090799 
Journal Article 
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis 
Sun, Yu; Liu, WenZ; Liu, Tao; Feng, Xu; Yang, Nuo; Zhou, HuaFu; , 
2015 
Yes 
Journal of Receptors and Signal Transduction
ISSN: 1079-9893 
TAYLOR & FRANCIS LTD 
ABINGDON 
600-604 
26096166 
WOS:000367812500014 
The generic mitogen-activated protein kinases (MAPK) signaling pathway is shared by four distinct cascades, including the extracellular signal-related kinases (ERK1/2), Jun amino-terminal kinases (JNK1/2/3), p38-MAPK and ERK5. Mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK) pathway is reported to be associated with the cell proliferation, differentiation, migration, senescence and apoptosis. The literatures were searched extensively and this review was performed to review the role of MAPK/ERK signaling pathway in cell proliferation, differentiation, migration, senescence and apoptosis.