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HERO ID
7103305
Reference Type
Journal Article
Title
Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate
Author(s)
Jacobsen, AC; Nielsen, S; Brandl, M; Bauer-Brandl, A; ,
Year
2020
Is Peer Reviewed?
1
Journal
Pharmaceutical Research
ISSN:
0724-8741
EISSN:
1573-904X
Language
English
PMID
32394114
DOI
10.1007/s11095-020-02807-x
Abstract
Here, first experiences with a prototype tool for high throughput (passive) permeability profiling, a 96-well plate comprising the Permeapad® membrane, are reported. The permeabilities of a set of drugs were determined and compared to published measures of oral absorption, such as human fraction absorbed (Fa) and in vitro permeability values obtained using other tools.
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