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HERO ID
7126441
Reference Type
Journal Article
Title
Association between blood lead levels and blood pressure in American adults: Results from NHANES 1999-2016
Author(s)
Teye, SO; Yanosky, JD; Cuffee, Y; Weng, X; Luquis, R; Farace, E; Wang, Li
Year
2020
Is Peer Reviewed?
Yes
Journal
Environmental Science and Pollution Research
ISSN:
0944-1344
EISSN:
1614-7499
Volume
27
Issue
36
Page Numbers
45836-45843
Language
English
PMID
32803607
DOI
10.1007/s11356-020-10381-3
Web of Science Id
WOS:000559954200003
Abstract
The aim of this study was to investigate the association between blood lead level (BLL) and hypertension in adults when lead exposure for the general population is low. The study used data from the US National Health and Nutrition Examination Survey (NHANES) 1999-2016. Participants aged 20 to 79 years were included in our study. Weighted multiple linear regression and logistic regression were conducted to test the association between BLL and systolic/diastolic blood pressure and hypertension status, respectively, while controlling for age, gender, race/ethnicity, body mass index, income level, and education. A total of 30,467 participants were included in this study. There was no association between BLL and hypertension status for the overall sample. Among those who were not taking antihypertensive medication, after adjusting for covariates, systolic blood pressure was positively correlated with BLL in non-Hispanic Whites (P = 0.004) and non-Hispanic Blacks (P = 0.0005), but not Hispanics (P = 0.07) nor Others (P = 0.37). The relationship between diastolic blood pressure and lead levels was also significant in non-Hispanic Whites and non-Hispanic Blacks. This study showed that higher BLL was associated with higher systolic and diastolic blood pressure in some population groups, but not associated with hypertension status.
Keywords
blood lead; NHANES; lead exposure; hypertension; high blood pressure; race factor
Tags
NAAQS
•
ISA - Lead (2024 Final Project Page)
Included in Peer Input Draft
Appendix 4 (Cardiovascular Effects)
Included in External Review Draft
Appendix 4 (Cardiovascular Effects)
Included in Final Draft
Appendix 4 (Cardiovascular Effects)
Title-Abstract Screening (SWIFT-AS) - Included
Title-Abstract Screening (SWIFT-AS) - Included
Full-Text Screening Included
Full-Text Screening Included
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