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7129388 
Journal Article 
HYDROGEN-DEUTERIUM EXCHANGE OF HISTIDINE AND HISTAMINE WITH DEUTERATED TRIFLUOROMETHANESULFONIC ACID 
Tachrim, ZP; Kurokawa, N; Tokoro, Y; Hashimoto, M; , 
2020 
Yes 
Heterocycles
ISSN: 0385-5414 
PERGAMON-ELSEVIER SCIENCE LTD 
OXFORD 
101 
1 
357-362 
WOS:000571527200028 
Histidine and its decarboxylated metabolite, histamine, containing imidazole ring, play an important role for biological activity. Deuterated trifluoromethanesulfonic acid (TfOD) is one of the acid hydrogen-deuterium exchange reagents for aromatic compounds. Hydrogen-deuterium exchanges of histidine and histamine with TfOD were examined in this report. 
Hydrogen-Deuterium Exchange; Histidine; Histamine; Imidazole; Triflic Acid 
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