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7145041 
Journal Article 
Janus particles for (bio)sensing 
Yanez-Sedeno, P; Campuzano, S; Pingarron, JM; , 
2017 
ELSEVIER SCIENCE BV 
AMSTERDAM 
276-288 
WOS:000417805400033 
This review article sheds useful insight in the use of Janus nanoparticles for (bio)sensing in connection with optical and electrochemical transduction. After a brief introduction of the main properties, types and fabrication strategies of Janus nanoparticles, selected applications for their use in electrochemical and optical biosensing are critically discussed. Highlighted examples illustrate the great versatility and interesting possibilities offered by these smart multifunctional nanoparticles for (bio)sensing of relevant analytes operating both in static and dynamic modes. Progress made so far demonstrate their suitability for designing single-or multiplexed (bio)sensing strategies for target analytes of different nature (organic and inorganic compounds, proteins, cells and oligomers) with relevance in clinical (H2O2, glucose, cholesterol, CEA, human IgG, propranolol, bacterial and tumor cells) and environmental (lead and organophosphorous nerve agents) fields. Key future challenges and envisioned opportunities of the use of Janus nanoparticles in the (bio)sensing field are also discussed. (C) 2017 Elsevier Ltd. All rights reserved.