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7147001 
Journal Article 
Review 
Intradiverticular bladder tumours: Review of the Cancer Committee of the French Association of Urology 
Neuzillet, Y; Soulie, M; Pfister, C; Comperat, E; Roupret, M; Larre, S; Roy, C; Quintens, H; Houede, N; Pignot, G; Wallerand, H; , 
2012 
1 
Progres en Urologie
ISSN: 1166-7087 
ELSEVIER MASSON, CORPORATION OFFICE 
PARIS 
22 
9 
495-502 
French 
22732640 
WOS:000306266200001 
Introduction. - Cancer Committee of the French Association of Urology (CCAFU) conducted a review of the epidemiology, diagnosis and treatment of intradiverticular bladder tumours (TVID) and proposed therapeutic management.Material and methods. - A bibliographic research in French and English using Medline (R) with the keywords "tumor", "bladder" and "diverticulum" was performed.Results. - TVID are more frequently of stage T >= 3a and with non urothelial histology than classical bladder tumors. At diagnosis, the risk of underestimation of the extent and multifocality of the tumor was described. Their prognosis, that was more pejorative than conventional tumors, should impelled to limit the indications of conservative treatment. The evidence levels of analyzed publications were low, with C level according to Sackett score.Conclusion. - the specificities of the TVID have lead the CCAFU to propose specific therapeutic guidelines, based on poor evidence level. Ta-T1 low grade TVID can be treated by transurethral resection alone or followed by BCG therapy in cases of associated carcinoma in situ. High-grade TVID, unifocal and without associated carcinoma in situ, can be treated by diverticulectomy associated with pelvic lymphadenectomy. High grade TVID, multiple or associated with carcinoma in situ, warranted total cystectomy. (C) 2012 Elsevier Masson SAS. All rights reserved.