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7176609 
Journal Article 
A Battery- and Leadless Heart-Worn Pacemaker Strategy 
Yi Zhiran; Qu Dan; Lang Xilong; Xu Zhiyun; Liu Jingquan; Zhang Hao; Yang Bin; Xie Feng; Tian Yingwei; Li Ning; Dong Xiaoxue; Ma Ye; Huang Yue; Hu Yili; Xu Xiaobin; , 
2020 
Yes 
Advanced Functional Materials
ISSN: 1616-301X
EISSN: 1616-3028 
WILEY-V C H VERLAG GMBH 
WEINHEIM 
WOS:000531350900001 
Over the past half-century, cardiac pacing technology has adhered to one basic system. However, many pacemaker-related complications are related to this system, particularly in terms of the power supply and leads. Here, for the first time a heart-worn pacemaker strategy is presented, which allows batteryless powering and leadless pacing. The batteryless feature is attained via heart-extrusion energy scavenging through a micromachined piezoelectric thick film transducer. A record in vivo output current of 30 mu A is obtained in an adult swine by the implanted piezoelectric transducer, which can effectively drive a commercial cardiac pacemaker. The exocardial pacing method is demonstrated by this batteryless pacemaker functions without a device or leads placed within the cardiac chambers. Lead- or batteryless options are being explored as new basic features of cardiac pacemakers. The presented heart-worn pacemaker strategy may be useful in future pacing technology.