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7182350 
Journal Article 
Cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: A two-centre tract of interest-based DTI analysis 
Müller, HP; Agosta, F; Gorges, M; Kassubek, R; Spinelli, EG; Riva, N; Ludolph, AC; Filippi, M; Kassubek, J; , 
2018 
ELSEVIER SCI LTD 
OXFORD 
1062-1069 
English 
After the demonstration of a corticoefferent propagation pattern in amyotrophic lateral sclerosis (ALS) by neuropathological studies, this concept has been used for in vivo staging of individual patients by diffusion tensor imaging (DTI) techniques, both in `classical` ALS and in restricted phenotypes such as primary lateral sclerosis (PLS).