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7182648 
Journal Article 
Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting 
Jalonen, J; Hynynen, M; Kuitunen, A; Heikkilä, H; Perttilä, J; Salmenperä, M; Valtonen, M; Aantaa, R; Kallio, A; , 
1997 
1 
Anesthesiology
ISSN: 0003-3022
EISSN: 1528-1175 
LIPPINCOTT WILLIAMS & WILKINS 
PHILADELPHIA 
86 
2 
331-345 
English 
9054252 
WOS:A1997WG82900009 
Alpha 2-adrenergic agonists decrease sympathetic tone with ensuing attenuation of neuroendocrine and hemodynamic responses to anesthesia and surgery. The effects of dexmedetomidine, a highly specific alpha 2-adrenergic agonist, on these responses have not been reported in patients undergoing coronary artery bypass grafting. 
sympathetic nervous system; alpha(2)-adrenergic agonists, dexmedetomidine, catecholamines; anesthesia, cardiac; anesthetics, intravenous, fentanyl; anesthetics, volatile, enflurane; outcome, cardiac, perioperative myocardial ischemia; surgery, cardiac, coronary artery bypass grafting; heart, blood pressure, hypertension; heart, heart rate 
9th Annual Meeting of the European Association-of-Cardiothoracic-Anaesthesiologists 
TURKU, FINLAND