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7184011 
Journal Article 
A role for helminth parasites in achieving immunological tolerance in transplantation 
Johnston, C; Mcsorley, H; Smyth, D; Anderton, S; Wigmore, S; Maizels, R; , 
2015 
1 
The Lancet
ISSN: 0140-6736
EISSN: 1474-547X 
English 
26312872 
Helminths infect more than a quarter of the world's population. Their success as parasites is the result of active immunomodulation of the host immune response, which can have benefits for the host, particularly in suppressing harmful allergic and autoimmune responses. Accordingly, we tested the hypothesis that helminth infection reduces the immune response to allograft transplantation.