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HERO ID
7186582
Reference Type
Journal Article
Title
Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders
Author(s)
Zhu, X; Xie, S; Xu, T; Wu, X; Han, M; ,
Year
2017
Is Peer Reviewed?
1
Journal
Molecular metabolism
ISSN:
2212-8778
Language
English
PMID
28580280
DOI
10.1016/j.molmet.2017.03.003
Abstract
Identification of additional regulatory factors involved in the onset of obesity is important to understand the mechanisms underlying this prevailing disease and its associated metabolic disorders and to develop therapeutic strategies. Through isolation and analysis of a mutant, we aimed to uncover the function of a Ras-GAP gene, Rasal2 (Ras protein activator like 2), in the development of obesity and related metabolic disorders and to obtain valuable insights regarding the mechanism underlying the function.
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