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7196948 
Journal Article 
Pseudomonas 2.0: genetic upgrading of P. putida KT2440 as an enhanced host for heterologous gene expression 
Martínez-García, E; Nikel, PI; Aparicio, T; de Lorenzo, V; , 
2014 
1 
Microbial Cell Factories
ISSN: 1475-2859
EISSN: 14752859 
English 
25384394 
Because of its adaptability to sites polluted with toxic chemicals, the model soil bacterium Pseudomonas putida is naturally endowed with a number of metabolic and stress-endurance qualities which have considerable value for hosting energy-demanding and redox reactions thereof. The growing body of knowledge on P. putida strain KT2440 has been exploited for the rational design of a derivative strain in which the genome has been heavily edited in order to construct a robust microbial cell factory.