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7219463 
Journal Article 
Impact of preformulation on drug development 
Bharate, SS; Vishwakarma, RA; , 
2013 
Yes 
Expert Opinion on Drug Delivery
ISSN: 1742-5247
EISSN: 1744-7593 
10 
9 
1239-1257 
English 
23534681 
Preformulation assists scientists in screening lead candidates based on their physicochemical and biopharmaceutical properties. This data is useful for selection of new chemical entities (NCEs) for preclinical efficacy/toxicity studies which is a major section under investigational new drug application. A strong collaboration between discovery and formulation group is essential for selecting right NCEs in order to reduce attrition rate in the late stage development. 
Drug development; Investigational new drug; Preformulation; Product recall