Health & Environmental Research Online (HERO)


Print Feedback Export to File
7232127 
Journal Article 
Evaluation of peptoid mimics of short, lipophilic peptide antimicrobials 
Green, RM; Bicker, KL; , 
2020 
Yes 
International Journal of Antimicrobial Agents
ISSN: 0924-8579 
English 
32540430 
Antimicrobial peptides are proving to be promising lead compounds for therapeutics. The major disadvantage of antimicrobial peptides is their proteolytic instability in the body, with half-lives averaging less than an hour. Peptoids, or N-substituted glycines, have emerged as a promising field of peptidomimetics by retaining the beneficial properties of antimicrobial peptides while improving their stability.