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HERO ID
7257652
Reference Type
Journal Article
Title
Fatty acid metabolism meets organelle dynamics
Author(s)
Walch, L; Čopič, A; Jackson, CL; ,
Year
2015
Is Peer Reviewed?
Yes
Journal
Developmental Cell
ISSN:
1534-5807
Language
English
PMID
25805129
DOI
10.1016/j.devcel.2015.03.008
Abstract
Upon nutrient deprivation, cells metabolize fatty acids (FAs) in mitochondria to supply energy, but how FAs, stored as triacylglycerols in lipid droplets, reach mitochondria has been mysterious. Rambold et al. (2015) now show that FA mobilization depends on triacylglycerol lipolysis, whereas autophagy feeds the lipid droplet pool for continued fueling of mitochondria.
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