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7269763 
Journal Article 
Review 
Skeletal fluorosis: don't miss the diagnosis! 
Sellami, M; Riahi, H; Maatallah, K; Ferjani, H; Bouaziz, MC; Ladeb, MF 
2020 
1 
Skeletal Radiology
ISSN: 0364-2348
EISSN: 1432-2161 
49 
3 
345-357 
English 
31501957 
Skeletal fluorosis is a rare toxic osteopathy characterized by massive bone fixation of fluoride. The disease occurs as an endemic problem in some parts of the world and is the result of prolonged ingestion or rarely by inhalation of high amounts of fluoride. Radiographic presentation is mainly characterized by bone changes with osteocondensation and later ossification of many ligaments and interosseous membranes. Skeletal fluorosis is not clinically obvious and can be confused with other rheumatologic disorders. Its severity lies in the development of skeletal deformities and neurological complications. Management of fluorosis generally focuses on symptom treatment. 
Index Medicus; Bone condensation; Imaging; Skeletal fluorosis; Ossification; Ossification, Heterotopic -- epidemiology; Osteosclerosis -- epidemiology; Humans; Ossification, Heterotopic -- diagnostic imaging; Ossification, Heterotopic -- chemically induced; Osteosclerosis -- diagnostic imaging; Osteosclerosis -- chemically induced; Bone Diseases, Metabolic -- diagnostic imaging; Bone Diseases, Metabolic -- epidemiology; Fluoride Poisoning -- diagnostic imaging; Fluoride Poisoning -- epidemiology; Bone Diseases, Metabolic -- chemically induced