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7306 
Journal Article 
The frequency of sister chromatid exchanges in human lymphocytes treated with ethanol and acetaldehyde 
Jansson, T 
1982 
Yes 
Hereditas
ISSN: 0018-0661
EISSN: 1601-5223 
97 
2 
301-303 
English 
7161122 
WOS:A1982PU27600015 
Ethanol is often used as solvent for substances tested for genetic toxicity, and lymphocyte cultures are frequently used as test systems. Therefore, the conflicting results on ethanol induced SCE and chromosomal aberrations in lymphocytes give serious problems in interpretation of results from tests where ethanol has been used as solvent. This investigation was made to clarify this situation and both ethanol and acetaldehyde were tested for their ability to induce SCE in human lymphocytes. In agreement with Ristow and Obe (1978) an increased frequency of SCE was found after treatment with acetaldehyde. Ethanol, however, did not affect the frequency of SCE. 
induction; effects on; ethanol; acetaldehyde; Genetics Abstracts; Toxicology Abstracts; Immunology Abstracts; chromosome aberrations; lymphocytes; sister chromatid exchange; genotoxicity testing; F 06780:Genetics; X 24221:Toxicity testing; G 07220:General theory/testing systems 
• Formaldehyde [archived]
     Reproductive and Developmental Effects
          Screened
               Title/abstract
                    Not developmental/reproductive
     Retroactive RIS import
          2015
               FA DevRepro 072115
                    Not Dev/Repro-Outcome Criteria
                         Not Dev/Repro-Outcome Criteria
• IRIS Formaldehyde (Inhalation) [Final 2024]
     Literature Indexing
          Other sources and cited references
     Literature Identification
          Reproductive and Developmental Effects
               Excluded