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733118 
Journal Article 
Clinical spectroscopy: Seventy cases of generalized argyrosis following organic and colloidal silver medication, including a biospectrometric analysis of ten cases 
Gaul, LE; Staud, AH 
1935 
Yes 
JAMA: Journal of the American Medical Association
ISSN: 0098-7484
EISSN: 1538-3598 
104 
16 
1387-1390 
English 
The alarming increase of argyrosis leaves little doubt as to our purpose in this report. There has been an accumulation of indubitable clinical evidence which makes it imperative to present before those who prescribe, dispense or use these drugs the danger entailed therein. It must be emphasized that within the past year, following intranasal applications with Argyrol and Neo-Silvol in fifteen children under 10 years of age, an argyrosis developed. Ten of these fifteen children were girls. All these children will present throughout their lives a conspicuous and permanent bluish or slate-gray discoloration that will select them as objects of whispered comments by friends and strangers. At present there is no treatment for argyria.