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HERO ID
735989
Reference Type
Journal Article
Title
[The effect of trichlorfon and dimethoate on the enzyme activity of the brain]
Author(s)
Nikolayev, KA
Year
1973
Is Peer Reviewed?
No
Journal
Veterinariya
ISSN:
0042-4846
Volume
3
Page Numbers
105-106
Language
Russian
Abstract
The effects of different concentrations of trichlorfon and dimethoate on the acetylcholinesterase and sodium-potassium-adenosine triphosphatase activity of rabbit brain homogenates were studied. The rates of acetylcholinesterase and sodium-potassium-adenosine triphosphatase inhibition due to 0. 009 M, 0. 0009 M, 0. 00009 M, and 0. 000009 M concentrations of trichlorfon were 100% and 84. 15%, 99. 1% and 61. 95%, 93% and 57. 7%, 71. 7% and 45. 5%, and 23. 15% and 36. 57%, respectively. The corresponding rates of acetylcholinesterase and sodium-potassium-adenosine triphosphatase inhibition due to identical dimethoate concentrations were 98. 1% and 90. 1%82. 7% and 71. 46%, 29% and 67. 86%, and 15. 8% and 44. 2%. The respective trichlorfon and dimethoate concentrations and the rates of the acetylcholinesterase and sodium-potassium-adenosine triphosphatase inhibition were directly related.
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