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7413770 
Journal Article 
Randomised controlled trial of the effects of L-ornithine on stress markers and sleep quality in healthy workers 
Miyake, M; Kirisako, T; Kokubo, T; Miura, Y; Morishita, K; Okamura, H; Tsuda, A; , 
2014 
Nutrition Journal
ISSN: 1475-2891 
BMC 
LONDON 
English 
L-ornithine is a non-essential, non-protein amino acid. Although L-ornithine is contained in various foods, the amount is usually small.Recently, studies have shown that orally administered L-ornithine reduced the stress response in animals.From these findings, we speculated that L-ornithine may play a role in the relieve of stress and improve sleep and fatigue symptoms in humans. Through a randomised, double-blind, placebo-controlled clinical study, we asked if L-ornithine could be beneficial to stress and sleep in healthy workers.