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7416275 
Journal Article 
Genome-wide mapping of copy number variations in commercial hybrid pigs using a high-density SNP genotyping array 
Zhou, LS; Li, J; Yang, J; Liu, CL; Xie, XH; He, YN; Liu, XX; Xin, WS; Zhang, WC; Ren, J; Ma, JW; Huang, LS; , 
2016 
1 
Russian Journal of Genetics
ISSN: 1022-7954
EISSN: 1608-3369 
MAIK NAUKA/INTERPERIODICA/SPRINGER 
NEW YORK 
85-92 
WOS:000369257400011 
Copy number variations (CNVs) are important forms of structural variation in human and animals and can be considered as a major genetic component of phenotypic diversity. Here we used the Illumina PorcineSNP60 BeadChip V2 and a DLY [Duroc x (Large White x Landrace)] commercial hybrid population to identify 272 CNVs belonging to 165 CNV regions (CNVRs), of which 66 are new. As CNVRs are specific to origin of population, our DLY-specific data is an important complementary to the existing CNV map in the pig genome. Eight CNVRs were selected for validation by quantitative real-time PCR (qRT-PCR) and the accurate rate was high (87.25%). Gene function analysis suggested that a common CNVR may play an important role in multiple traits, including growth rate and carcass quality.