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Citation
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HERO ID
7417070
Reference Type
Journal Article
Title
Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns
Author(s)
Kirby, MK; Ramaker, RC; Roberts, BS; Lasseigne, BN; Gunther, DS; Burwell, TC; Davis, NS; Gulzar, ZG; Absher, DM; Cooper, SJ; Brooks, JD; Myers, RM; ,
Year
2017
Is Peer Reviewed?
Yes
Journal
BMC Cancer
ISSN:
1471-2407
EISSN:
14712407
Publisher
BMC
Location
LONDON
Language
English
PMID
28412973
DOI
10.1186/s12885-017-3252-2
Web of Science Id
WOS:000399668700002
URL
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3252-2
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Abstract
Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic modification that is detectable in peripheral patient fluids such as urine and blood plasma that could serve as a non-invasive diagnostic biomarker for prostate cancer.
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