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7422154 
Journal Article 
Aging and Intrinsic Aging: Pathogenesis and Manifestations 
Assaf, H; Adly, MA; Hussein, MR; , 
2017 
Springer Berlin Heidelberg 
Berlin, Heidelberg 
Textbook of Aging Skin 
783-794 
As the population ages, dermatological focus must shift from ameliorating the cosmetic consequences of skin aging to decreasing the genuine morbidity associated with problems of the aging skin. Therefore, a better understanding of both the intrinsic and extrinsic influences on the aging of the skin, as well as distinguishing the retractable aspects of cutaneous aging (primarily hormonal and lifestyle influences) from the unretractable cutaneous aging (primarily intrinsic aging), is critical to solve the problem of aging.