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7425761 
Journal Article 
Review 
Mebendazole in parasitic infections other than those caused by soil-transmitted helminths 
Cañete, R; Escobedo, AA; Almirall, P; González, ME; Brito, K; Cimerman, S; , 
2009 
1 
Transactions of the Royal Society of Tropical Medicine and Hygiene
ISSN: 0035-9203 
OXFORD UNIV PRESS 
OXFORD 
103 
5 
437-442 
English 
19195670 
WOS:000265822400002 
Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence that this drug, taken at higher doses than used for STH and enterobiasis, could be sufficiently effective on some protozoa, nematodes and cestodes. 
Benzimidazole; Children; Helminths; Mebendazole; Parasites; Therapy; albendazole sulfone; albendazole sulfoxide; benzimidazole; chloroquine; cotrimoxazole; mebendazole; mepacrine; metronidazole; niclosamide; nitazoxanide; omeprazole; ornidazole; paromomycin; praziquantel; quinine; secnidazole; tiabendazole; tinidazole; abdominal discomfort; abdominal pain; ascariasis; Ascaris; Capillaria; Coccidia; coccidiosis; cryptosporidiosis; Cryptosporidium; Cryptosporidium parvum; Cyclospora cayetanensis; cyclosporiasis; dosage schedule comparison; drug activity; drug dose comparison; drug efficacy; drug mechanism; drug megadose; drug tolerability; echinococcosis; Echinococcus granulosus; Echinococcus multilocularis; Encephalitozoon intestinalis; enterobiasis; Enterobius; Enterobius vermicularis; Giardia lamblia; giardiasis; helminthiasis; hookworm; human; hymenolepiasis; Hymenolepis nana; Isospora belli; isosporiasis; malaria; Mansonella perstans; Microsporida; microsporidiosis; nausea; parasitosis; Plasmodium falciparum; review; Strongyloides; Taenia saginata; Taenia solium; taeniasis; Toxocara; Trichinella; trichinosis; Trichomonas vaginalis; trichomoniasis; Trichuris; vomiting; Adolescent; Animals; Antiparasitic Agents; Child; Child, Preschool; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Giardiasis; Helminthiasis; Humans; Malaria; Male; Mebendazole; Treatment Outcome; Trichomonas Vaginitis; Cestoda; Nematoda; Protozoa; Vermes 
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