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7433291 
Journal Article 
Further experience with mebendazole in the treatment of symptomatic trichuriasis in children 
Scragg, JN; Proctor, EM; , 
1978 
Yes 
American Journal of Tropical Medicine and Hygiene
ISSN: 0002-9637
EISSN: 1476-1645 
27 
2 I 
255-257 
English 
646017 
Mebendazole (methyl-5-benzoylbenzimidazole-2-carbamate: Vermox), a broad spectrum anthelmintic, cured 22 (88%) children with symptomatic trichuriasis when given as a single 6-day course in a dosage of 100 mg twice daily. A further 3 (12%) were cured after a repeat 6-day course of therapy. Thus complete parasite eradication was achieved in all. The administration of an antidiarrheal agent, loperamide hydrochloride (Imodium), appeared to enhance the efficacy of mebendazole. Both drugs were well tolerated and completely free of any toxic effects. 
loperamide; mebendazole; drug response; drug therapy; geographic distribution; nematode; oral drug administration; school child; South Africa; therapy; trichuriasis; Trichuris 
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