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7433799 
Journal Article 
Malnutrition, Cachexia, and Quality of Life in Patients with Cancer 
Grundmann, O; Yoon, SL; Williams, JJ; , 
2019 
Springer International Publishing 
Cham 
Handbook of Famine, Starvation, and Nutrient Deprivation 
943-959 
Cancer has become one of the most common and devastating health problems in the aging population worldwide. Patients often suffer from a range of complications associated with cancer and cancer treatments that impact their quality of life and may reduce overall survival. Among those secondary to cancer and treatment are malnutrition and cachexia, which may be a result of the malignancy itself or of the treatment approaches, especially chemotherapy. Depending on the specific cancer type and stage, the prevalence of cachexia ranges from 28% to 57% as evaluated by clinical trials. This chapter will address the following topics related to malnutrition and cancer cachexia:Contributing factors to the development of malnutrition and cachexiaUnderlying pathophysiology and biochemical derangementPotential biochemical screening markers for malnutrition and cachexiaCurrent and future treatment approaches and preventative strategies