Health & Environmental Research Online (HERO)


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7434073 
Journal Article 
Prognostic and Predictive Factors 
Tuzlali, S; Yavuz, E; , 
2019 
Springer International Publishing 
Cham 
Breast Cancer 
171-186 
A variety of pathological parameters are used to assess prognosis and predict therapeutic response for breast cancer patients. These parameters include tumor size, axillary lymph node status, histological features, hormone receptor status, HER2 status and the proliferative capacity of the tumor. Several gene expression profiling assays have been developed in an attempt to predict the survival and response to therapies of breast cancer patients. These assays are based on the identification of prognostic gene signatures by using microarrays. Many groups have attempted to develop genomic tests based on genomic profiling to improve the prediction of clinical outcome compared with standard pathological and clinical markers.