GENERATION OF A CONFIGURATIONALLY STABLE CHIRAL BENZYLLITHIUM DERIVATIVE, AND THE CAPRICIOUS STEREOCHEMISTRY OF ITS ELECTROPHILIC SUBSTITUTION | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

7435987

Reference Type

Journal Article

Title

GENERATION OF A CONFIGURATIONALLY STABLE CHIRAL BENZYLLITHIUM DERIVATIVE, AND THE CAPRICIOUS STEREOCHEMISTRY OF ITS ELECTROPHILIC SUBSTITUTION

Author(s)

Hoppe, D; Carstens, A; Kramer, T

Year

1990

Is Peer Reviewed?

Journal

Angewandte Chemie: International Edition in English
ISSN: 0570-0833

Publisher

VCH PUBLISHERS INC

Location

DEERFIELD BEACH

Volume

Issue

Page Numbers

1424-1425

Language

English

DOI

10.1002/anie.199014241

Web of Science Id

WOS:A1990EU00600022

Abstract

Depending on the electrophile, substitution of the chiral benzyllithium compound 2, which is configurationally stable in solution, takes place with retention or inversion of configuration. 2 was generated by deprotonation of the Corresponding optically active benzyl carbamate 1. The products 3 are of interest as synthetic building blocks. Cb ï£¾ C(ï£¾O)NiPr2. (Figure Presented.) Copyright Â© 1990 by VCH Verlagsgesellschaft mbH, Germany