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7436494 
Journal Article 
Prostate Cancer: Role of Conventional Radionuclide and Hybrid Bone Imaging 
Beheshti, M; Langsteger, W; , 
2012 
Springer Berlin Heidelberg 
Berlin, Heidelberg 
Radionuclide and Hybrid Bone Imaging 
635-659 
Bone is the second most common site of metastatic disease after lymph nodes in prostate cancer. This is related to a poor prognosis and is one of the major causes of morbidity and mortality in patients with prostate carcinoma. Early detection of osseous metastases and the definition of its extent, pattern and aggressiveness are crucial for proper staging and restaging; it is particularly important in high-risk primary disease before embarking on radical prostatectomy or radiation therapy.